Yeouido, Seoul, Korea
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Rejuran & Skin Boosters

What Is Rejuran? A Plain-English Guide to the Skin Booster

What is Rejuran? A polynucleotide skin booster injected into the dermis. Learn what it is made from, what it targets and how a Seoul clinic plans treatment.

Doctor at Time Return Clinic in Seoul explaining Rejuran skin booster treatment

What is Rejuran? Rejuran is a skin booster. It is injected into the dermis to improve skin quality, not to add volume.

The active ingredient is polynucleotide (PN) extracted from salmon DNA. It is made by the Korean company PharmaResearch.

What Rejuran is used for

Doctors use the Rejuran skin booster for skin that looks thin, dry, rough or tired.

  • Fine lines and loss of elasticity
  • Dull or dehydrated texture
  • Acne scars and uneven texture
  • Skin stressed by masks, irritation or acne

What is in Rejuran

The ingredient is a polynucleotide, a chain of DNA fragments, taken from salmon. People search for it as Rejuran salmon DNA, PN or PDRN.

Your doctor chooses the product line and the injection depth based on your skin. Not every Rejuran product is meant for the same area, which is why a consultation comes first.

How a Rejuran treatment works

  1. Consultation. The doctor checks skin thickness and condition.
  2. Numbing. We use plasma 5-step anesthesia (5A+). See is Rejuran painful.
  3. Injection. Rejuran goes into the dermis. With Rejuran Healer the doctor injects by hand, point by point.
  4. Aftercare. You get instructions for the days after.

Is Rejuran a filler?

No. A filler adds volume. Rejuran is a skin booster aimed at skin quality: texture, elasticity and hydration. Doctors often plan it together with lifting.

How many sessions?

The doctor sets the number and spacing after examining your skin thickness and goals. We do not promise a fixed number before that assessment. Results vary by individual.

Why the doctor matters

The dermis is only about 0.5–2 mm thick. Reaching it evenly is a skill, which is why the same genuine product can give different results. Read why results differ.

Rejuran at Time Return Clinic

We are a Rejuran SVIP clinic selected by PharmaResearch and a 2026 Rejuran BLACK Membership clinic. Dr. Kim Yoo-ju is a certified Rejuran Healer Expert. Start with our guide to Rejuran Korea.

Questions we get about what is rejuran

What is Rejuran made from?
Rejuran contains polynucleotide (PN) extracted from salmon DNA. It is made by the Korean company PharmaResearch.
Is Rejuran a filler?
Rejuran is a skin booster aimed at skin quality. It is not used to add volume the way a filler is.
How many sessions do I need?
The doctor sets the number and spacing after examining your skin thickness and goals. Results vary by individual.

Results vary by individual. Every procedure carries the possibility of side effects, explained before you agree to treatment. This article is general information from the clinic, not a diagnosis. Suitability is decided at the consultation.

Premium Rejuran is Time Return.

  • Premium Rejuran film 1

  • Premium Rejuran film 2

Written by

Dr. Kim Yoo-ju, Rejuran Expert and founder of Time Return Clinic in Seoul

Dr. Kim Yoo-ju

Founder & Medical Director · Time Return Clinic

  • Patent holder: collagen-film thread lifting; also holds Korea’s only body thread lifting patent
  • Rejuran clinical advisor and Rejuran Expert
  • Thermage clinical advisor and TTT Master
Full profile
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